Ide99: Ide N, Ikebe T, Kutsukake K (1999). "Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals." J Mol Biol 333(2) 261-78. ![]() Huerta03: Huerta AM, Collado-Vides J (2003). "GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli." Microbiology 150(Pt 1) 61-72. Hommais04: Hommais F, Krin E, Coppee JY, Lacroix C, Yeramian E, Danchin A, Bertin P (2004). "DNA sequence analysis suggests that expression of flagellar and chemotaxis genes in Escherichia coli and Salmonella typhimurium is controlled by an alternative sigma factor." Proc Natl Acad Sci U S A 84(18) 6422-4. Helmann87: Helmann JD, Chamberlin MJ (1987). "Transcriptional regulation of flhDC by QseBC and sigma (FliA) in enterohaemorrhagic Escherichia coli." Mol Microbiol 57(6) 1734-49. "Coupling of flagellar gene expression to flagellar assembly in Salmonella enterica serovar typhimurium and Escherichia coli." Microbiol Mol Biol Rev 64(4) 694-708. Ĭhilcott00: Chilcott GS, Hughes KT (2000). MatA- fliCp regulatory interaction was identified in Escherichia coli strain IHE 3034. MatA (MatA DNA-binding transcriptional dual regulator) ![]() GadE (GadE DNA-binding transcriptional activator) H-NS (H-NS DNA-binding transcriptional dual regulator) Regulation with unknown or unspecified binding site location: Position relative to start of first gene (fliC): RNA polymerase, sigma 28 (sigma F) factorĪbsolute Position of Transcription Start Site: showed in 1997 that transcription of fliC is highly dependent on alternative factor σ F and can be transcribed by RNA polymerase σ 28 in vitro ![]() Thus, we assigned a putative transcription start site for this promoter based on the observation that the majority of the σ 28 promoters, determined experimentally, present an important -10 motif (5'-CGA-3') at the -12 to -10 positions and a distance of 6 nucleotides between the transcription start site and the -10 box The sequence of this promoter has been defined, by computational analyses, from the consensus sequence of the σ 28 (σ F) promoters TAAAGTTT in the -35 box and GCCGATAA in the -10 box Roll the mouse over any element in the diagram for more information. Key to regulator colors: Green: activator Magenta: inhibitor Brown: dual Gray: unspecified.Ī dashed outline for a transcription factor binding site or a dashed promoter indicates a lack of high quality evidence for the Click on a binding site (if any) to navigate to the page for its transcription factor.Ĭlick on a gene to navigate to its gene page.
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